- EVALUATION OF PHOTOAGING ACTIVITY
Hyperpigmentations are particular concern to woman and the development of tests able to study the skin brightening are very important. Experiments are based on the inhibition of human tyrosinase using human epidermal melanocytes .
- EVALUATION OF THE MAMMALIAN CELL MICRONUCLEUS TEST
The in vitro micronucleus assay is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells. This test helps to detect the activity of clastogenic and aneugenic chemicals in cells that have undergone cell division during or after exposure to the test substances, following the OECD guideline 487.
- EVALUATION OF ADIPOGENIC ACTIVITY
Using 3T3-L1 cells, the new tests are addressed to study the mechanism of cosmetic products to induce adipocyte differentiation and adipogenesis.
- MCROBIOLOGICAL EXPERIMENTS